What Every Therapist Should Know About Ketamine Infusion Therapy
November 4, 2025

What Every Therapist Should Know About Ketamine Infusion Therapy


At Sage Health & Wellness, we partner with mental‑health professionals to support their clients and patients in achieving deeper breakthroughs. This blog is intended for therapists, psychologists, and other mental‑health providers who want to understand how ketamine infusion therapy (KIT) works, how it can be integrated into therapeutic care, and how Sage Health & Wellness supports clients safely and effectively.

An Introduction to Ketamine Infusion Therapy

Ketamine is a medication originally developed as an anesthetic, but in recent years low‑dose infusion protocols have emerged as a rapid‑acting treatment option for challenging psychiatric conditions — especially those that have not responded to more traditional interventions. PMC+3Columbia Irving Medical Center+3PMC+3 For therapists who are guiding clients with “treatment‑resistant” depression, anxiety, PTSD or suicidal ideation, it offers a new tool in the toolbox rather than a replacement for psychotherapy.

At Sage Health & Wellness, our ketamine infusion program is conducted in a medically supervised environment with board‑certified providers, and is designed to be integrated with ongoing psychotherapy/therapeutic support. We encourage you, as the therapist, to consider how this approach might complement your work.

Why Therapists Should Pay Attention

  • Rapid onset of effect: Unlike traditional antidepressants, which may take weeks, low‑dose ketamine infusions can yield meaningful improvement in mood and anxiety within hours to days. PMC+1

  • Effective for “hard‑to‑treat” cases: Studies indicate that for patients who have had limited benefit from standard treatments, ketamine infusion therapy shows significantly higher response rates. PMC+1

  • Potential to enhance psychotherapy: By reducing emotional reactivity, increasing neuroplasticity, and giving clients a “reset” of sorts, ketamine infusion therapy may make your work — e.g., trauma processing or cognitive restructuring — more effective.

  • Collaborative model benefits: When therapists work in tandem with infusion clinics, clients receive a more cohesive care plan and you retain your role as primary mental‑health clinician.

How The Process Works

Here’s what clients can expect — this is the context you’ll want to discuss with them in preparation:

  1. Initial consultation and screening: We assess medical history, psychiatric history, suitability (e.g., prior treatments tried, comorbidities), and collaborate with you as the therapist to make it safe and coordinated.

  2. Infusion sessions: Sessions typically last about 45 to 60 minutes for the infusion itself, within a controlled outpatient setting under constant monitoring (vitals, heart rate, blood pressure). After the infusion, clients are observed for 15‑30 minutes (or more) until medically cleared. Midwest Institute for Hearts and Minds+1

  3. Integration phase: After the infusion the therapist’s role becomes even more important. We encourage your client to bring emergent insights, shifts in mood or behavior, or new clarity into your therapy work.

  4. Maintenance and follow‑up: Some clients benefit from a series of infusions initially, followed by “booster” sessions at intervals. The exact schedule depends on individual response. New Pathways Clinic+1

Common Questions & How You Can Reassure Your Patients

Q: Is ketamine safe?
A: Yes, when administered in a clinical setting by trained professionals the safety profile is very good. Clients are continuously monitored, and we have medical staff on‑site at Sage to address any immediate issues. Side‑effects (e.g., transient dizziness, mild dissociation, nausea) are short‑lived. Midwest Institute for Hearts and Minds+1

 Q: Who is a good candidate?
A: Typically, individuals who have had one or more standard treatments (therapy, medications) with limited response, and for whom persistent depression, anxiety, or trauma symptoms are interfering with functioning. For any client you're working with who fits that description, exploring referral may make sense. Importantly: this is not a replacement for psychotherapy — it’s a complement. Harvard Health

Q: Will they respond immediately and forever?
A: Many clients experience relief quickly, sometimes within hours, but response varies. The effects may require augmentation with your ongoing therapy and possibly maintenance infusions. It’s realistic to frame it as “another way to accelerate or enhance your therapy” rather than a guaranteed cure. Veterans Affairs+1

Q: How will I, as a therapist, stay involved?
A: We encourage you to remain a central part of the client’s care. We coordinate with you (with client’s consent) so you know when infusions are happening, how the client is responding, and can help them integrate what arises. At Sage we can help by providing summary notes or updates (with consent) so you remain informed.

Q: What happens after the infusion in terms of therapy?
A: One of the main opportunities is that your client may arrive in session with new energy, new clarity, or a shift in perspective. You can help them harness that momentum immediately — for instance, deeper exploration of trauma, strengthened engagement with treatment, or quicker movement through stuck patterns.

Q: How many sessions will be required?
A: While each individual has their own path, many protocols begin with a series of 4–6 infusions over 2–3 weeks, followed by reassessment and possible maintenance. Powers Health+1

Why Choose Sage Health & Wellness

At Sage, we have built our ketamine infusion program with therapist‑collaboration front of mind. When you refer a client to us:

  • We provide a medically supervised infusion environment with safety and comfort prioritized.

  • We coordinate with therapists to ensure continuity of care and maximize the integration of your therapeutic work with the infusion outcomes.

  • We focus on supporting your client’s goals — improved engagement in therapy, reduction in symptoms, increased stability and readiness for deeper work.

  • Our intention is not just symptom relief, but helping the client leverage the infusion experience into real‑life transformation, which you as the therapist then build on.

If you have a client who’s been stuck, tried multiple medications or therapies with limited progress, or is experiencing severe symptoms (including suicidal thoughts) and you believe they could benefit from an accelerated intervention option, we invite you to discuss a referral with us at Sage. Together we can offer a comprehensive care path that combines the best of psychotherapy and innovative infusion treatment.

Closing Thoughts

As a therapist you’ve likely seen the frustration of clients who feel stuck despite all the work. The infusion model offered by Sage is not an alternative to your expertise, but a powerful adjunct — a way to complement your therapy with a medically supported intervention that opens new possibilities. If you’re looking for a partner who values your role, coordinates closely, and helps clients take a meaningful leap forward, we welcome you to explore the ketamine infusion program with Sage Health & Wellness.

For questions about referral protocols, client suitability, or to set up a consultation with our medical team, please contact us at Sage — we’re here to support you and your clients.

Sources

  1. “The Role of Ketamine in Treatment‑Resistant Depression.” PMC. PMC

  2. “Efficacy of Ketamine Therapy in the Treatment of Depression.” PMC. PMC

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